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December 19th, 2008 at 1:55 pm
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It encompasses a range of health care practices evolved to maintain and restore health by the prevention and treatment of illness.
Contemporary medicine applies health science, biomedical research, and medical technology to diagnose and treat injury and disease, typically through medication, surgery, or some other form of therapy.
The word medicine is derived from the Latin ars medicina, meaning the art of healing.
Though medical technology and clinical expertise are pivotal to contemporary medicine, successful face-to-face relief of actual suffering continues to require the application of ordinary human feeling and compassion, known in English as bedside manner.
As science and technology developed, medicine became more reliant upon medications. Pharmacology developed from herbalism and many drugs are still derived from plants (atropine, ephedrine, warfarin, aspirin, digoxin, vinca alkaloids, taxol, hyoscine, etc). The first of these was arsphenamine / Salvarsan discovered by Paul Ehrlich in 1908 after he observed that bacteria took up toxic dyes that human cells did not. Vaccines were discovered by Edward Jenner and Louis Pasteur. The first major class of antibiotics was the sulfa drugs, derived by French chemists originally from azo dyes. This has become increasingly sophisticated; modern biotechnology allows drugs targeted towards specific physiological processes to be developed, sometimes designed for compatibility with the body to reduce side-effects. Genomics and knowledge of human genetics is having some influence on medicine, as the causative genes of most monogenic genetic disorders have now been identified, and the development of techniques in molecular biology and genetics are influencing medical technology, practice and decision-making.
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Sahachiro Hata discovered the anti-syphilitic activity of this compound in 1908 in the laboratory of Paul Ehrlich, during a survey of hundreds of newly synthesized organic arsenical compounds. Ehrlich had theorized that by screening many compounds a drug could be discovered with anti-microbial activity. Ehrlich’s team began their search for such a “magic bullet” among chemical derivatives of the dangerously toxic drug atoxyl. This was the first organized team effort to optimize the biological activity of a lead compound through systematic chemical modifications, the basis for nearly all modern pharmaceutical research.
Arsphenamine was marketed under the trade name Salvarsan in 1910. It was also called 606, because it was the 606th compound synthesized for testing Germany it was the practice to designate compounds by their development number. Another compound known commonly in Germany by its number is Parathion, which was the 605th compound to be developed in search for insecticide. It is commonly known as E605 (E stands for Entwicklungsnummer (German for “development number”)]. Salvarsan was the first organic anti-syphillitic, and a great improvement over the inorganic mercury compounds that had been used previously. A more soluble (but slightly less effective) arsenical compound, Neosalvarsan, (neoarsphenamine), became available in 1912. These arsenical compounds came with considerable risk of side effects, and they were supplanted as treatments for syphilis in the 1940s by penicillin.
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Hello.
The images were released to celebrate the arrival on Monday of Emma Tallulah, the couple’s third daughter.
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September 27th, 2008 at 9:35 pm
Hello geneTorne!
As you ask…part of article:
If you are using any of these medications, you may not be able to receive the vaccine, or may need to wait until the other treatments are finished.
Do not start using a new medication without telling your doctor. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. There may be other drugs that can affect Gardasil. Tell your doctor about all the prescription and over-the-counter medications you have received.
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January 16th, 2008 at 12:54 pm
Upps! A guestbook. So I have to sign in. It ist boring in my hotel!
Crazy page!
Kind regards from Bamberg/Germany
Micha
June 21st, 2007 at 5:16 am
Robert and Theresa,
Thanks for mentioning White Swan Inn in your posting. Hopefully, next summer there will be an extension of the White Lake Pathway (new since you were in the area to research Bed, Breakfast, Bike Midwest) into Muskegon to join up with the new Lakeshore Trail. Lake Express ferry has been a great conduit for bicyclists traveling from Wisconsin. Safe rides and lots of tail winds! Enjoy the summer!
Cathy Russell, White Swan Inn, Whitehall, MI
June 20th, 2007 at 5:59 pm
It was nice meeting you today on the Muskatawa trail and we hope you enjoyed lunch in Marne. We look forward to reading about your adventures.
June 20th, 2007 at 4:30 pm
Hi Rob and Theresa, I am just catching up on your trip journal. A great story to tell for generations….
June 19th, 2007 at 1:43 pm
Robert and Theresa–I am catching up on your journal…sounds like the tour is going well…you both look great and 3 flats is not bad at all! The pic from the day you rode from Winsted to Minneapolis has some AT&T marker poles in it…not-very-pretty white ones with orange tops…my son and I GPS’d over 600 miles of those between SLC and Sacramento.
Take care-
Cindi
June 18th, 2007 at 10:35 pm
Hello Robert and Theresa,
Wow! Our little trip from Elroy to Sparta and back is now officially cool since we actually have a picture of it on the internet! Hope your trip is progressing well. We made to Sparta and had camp pitched before dark, then spent Sunday morning waiting out the rain. We got back to Elroy after dark and enjoyed a huge display of fireflies. I think Elroy must be the firefly capital of the world. The children did great going through the tunnels. They really enjoyed the down grade runs and were full of encouragement to go faster when we were on the up grades. Really, when you think of it, what’s there not to like about getting pulled around by Mama and Daddy and not having to do any of the work?
It is really great to see you doing a trip like this together. Our little ride was the first bike trip we have taken together other than just going around town, and with as well as it went, it probably won’t be the last. Thanks for stopping and visiting with us. Hope your trip across the Mitten is uneventful and pleasant.
June 15th, 2007 at 1:04 pm
Theresa: You are a goddess! What an extreme way to get in shape (I know that’s not the reason you’re doing this but I can’t help admiring that aspect).
Give me a jingle when you’re getting close to Madison, WI. It’s just as hot here as everywhere else. I’m near a bike path and could hoist my hefty self onto my padded bike seat and huff and puff through a few miles to meet you and then have a coronary, but if you know CPR what the heck, let’s do it.
Too bad our lakes are so polluted or we could visit in a cool liquid medium.
Judy
June 13th, 2007 at 8:19 am
Robert,
Mike and I met you at the Selby Inn. Man, the weather the very next day was amazingly bad for bicycles. 40-80mph from the north, lots of rain. We almost lost our kayak trailer - it lifted 4′ off the ground, totally freaking us out. Wind didn’t slow down until almost dark. We wondered how you were getting by.
You are approaching my town of Madison, WI about now. Let me know if you guys need any assistance, or route planning, as you work your way towards Milwaukee. I could potentially post maps on my web site for you if needed.
Tim Goode
608.438.8907
June 5th, 2007 at 11:31 am
It’s about time you guys biked across the country–I have trouble believing it’s been nine years since I did it (and 10 years since I graduated MVCDS!). Looks like you guys are having fun–too bad you’re not coming near Washington, DC, but maybe next time you’ll bike down the east coast. My brother is certainly jealous, as he’s never gone cost to coast, and now that he has a 6-month old son, looks like it might be a while until he gets the chance…
Keep spinning,
Michael Gerber
May 29th, 2007 at 3:55 pm
Hi. Robert and Theresa. It was great meeting and talking with you while you were in Forsyth. Keep spreading the word that Custer Country has lots of changing scenery. As Dorothy found out, “You’re not in Kansas…!”
Keep in touch. I’ll look forward to your return trip….oops, you’ll probably want to throw the bikes in the ocean by the time you get to Portland, Maine. Enjoy the rest of your trip and be careful out there.
Jim
May 26th, 2007 at 7:57 pm
love your site and am inspired and amazed at people like you who take the time to enjoy this beautiful country. Look forward to reading more.
May 21st, 2007 at 10:40 am
I have been inspired to do more biking now. The weather has to be right for me though.
May 14th, 2007 at 4:33 am
Theresa and Rob,
Nice travelogue! One of our daughters and I will fly into Portland June 12 and stay with friends in Corvallis as a staging point for departure. Our trip begins in Newport, Oregon and we will trace a Northern route that passes through Michigan, where my parents will be running their day camp for the “58th” year. We hope to also have web updates along the way using our Nokia N800 web tablet. Great to read of your adventures.
Cycle On…
May 12th, 2007 at 11:44 am
Thanks for stopping in for some iced tea at the Buster House in Pomeroy. Wish you luck and safety on the rest of your trip.
Hope you enjoyed the Alpowa Pass today. It’s “good” practice for the ride through eastern Idaho and the Lolo.
John
May 11th, 2007 at 11:11 am
Hi Rob & Theresa !
It was great having you as a guest of our hotel. We all have so much respect for the challenge you have taken on ! We will be following your journey.
Wishing you safe biking !
Mark Blotz
General Manager / Clover Island Inn
Kennewick, Wa.
May 9th, 2007 at 3:32 pm
Holy cow! I did a couple long bike rides a few times, but those only lasted a few days. And, it took weeks for my butt to recover. Hope you kids are taking good care of your backsides!
May 8th, 2007 at 9:15 pm
“Hey you guys,” something said in the movie “goonies” Kids were glad to finally meet both of you, 2 of them for the 1st time 11 and 16 year olds. One day they might meet some of the others on the east coast, only time will tell… Hope you all enjoyed the Oregon coast !! We do and will most likely never leave it.. We will follow your trip so if we ever do something like that: Highly unlikely, we can check the route and get some insights.. .Enjoy the short ride and take it easy.. Lator, dude and dudette
May 7th, 2007 at 11:46 pm
Hi Theresa and Rob!
It was really nice meeting you both, and touring you around.
I am hooked to the blog and will enjoy reading it every morning before work. And I will remember your wise recommendations for my future trip across the continent, one day!
Hope to see you again,
Veronique.
May 5th, 2007 at 5:10 am
I’m enjoying your entries and look forward to more podcasts. I am really, really impressed with what you’re doing. I’m glad you’ve made it possible for us to share your adventures along the road.
April 29th, 2007 at 2:00 pm
I am so impressed by your ambition, energy and willingness to defer other parts of your life to achieve this goal. We’re nowhere near your route (coast-to-coast cyclists tend to avoid Colorado), but I’ll be checking out your site often and rooting for you all the way, from the time you see the Pacific in your rearview mirror until the Atlantic is in your line of light. (Apologies for clicking on “submit” before I was finsihed.)
April 29th, 2007 at 1:58 pm
I am so impressed by your ambition, energy and willingness to defer other parts of your life to achieve this goal. We’re nowhere near your route (coast-to-coast cyclists tend to avoid Colorado), but I’ll be checking out our site and rooting for you all the way.
April 28th, 2007 at 4:00 pm
Just a few words of caution from a veteran who did an X/c ride at the age of 50 –
1)take it easy if you can the first couple of days and you can ride
yourself into shape. If you push too hard, you’ll make yourself sore & tired.
2/ I had insomnia on my trip. If Ambien had been available (I don’t
think it was on the scene yet) I would have brought a supply, just in case.
3/ you are avoiding western Pennsylvania, it seems. That’s GOOD.
Mountains there are not high but roads are not graded gently in the
northeast, as they are in the west. So prepare for steep climbs in
places you don’t expect… like Ohio & New York
Have a blast! I’m going to check your blog regularly.
Claire Walter’s friend Grace
October 27th, 2006 at 10:22 am
Theresa–I saw your post on the phred list…I’m not sure if I’ve seen all of your inquiries on the list, and just now came across you website. I live in Vancouver, WA and if I can be of any assistance to you concerning your trip–even a ride out to Astoria w/ your bikes and gear…let me know.
Cheers-
Cindi
October 26th, 2006 at 8:55 am
I started reading this at work, but since I’m at work, I’ll have to finish reading it later. It is interesting! I’m going to share the website with my friend who lives in Park City, UT. She is a serious cyclist. In fact, she just got back from a bike trip in Ireland.
October 21st, 2006 at 11:47 am
hey, I’m at hobart college up in geneva NY now, I’d like to try and ride with you guys if the times line up.
October 20th, 2006 at 5:51 pm
What? I am still looking for the dates of the trip. I would like to ride along with you in the Toledo area. I will ink some later, after I find the trip dates. Best of health and I wish I could be with you.
October 12th, 2006 at 9:30 pm
Told you I would check it out!